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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b603b53189625f211e0a0add0fa13ca0fd950b024be819a7caf297f8b1f0d6f' 
  AND token = 'iEhOf1j7DGw7l9rzKECpZuB2l2wYjUGU6GknZlHxo84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}