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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c585ecf708ac92b6cce7272a194d2a640e17a64315c593c6b8a89da2216f71e1' 
  AND token = 'Bhi9z0P9l4dfpT+38mnMDKVMUIsrejiRxgX7DjoJ6K4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}