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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0cb804ee31cfbe40b95813462af594113e5c02cb27e8565e5f90e28b294ae1b' 
  AND token = 'UB/ifHpBsa8MZdnQ8KwCWnaLUbYgFnmlbAu9ZjQRPOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}