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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fb65738366b8dd0e27c88e59c0e999361812836ebcc53ae016a982663e2e2f0' 
  AND token = '6wQ/amtuPKvgJb6BfEaSx1DWUfYCUtO4xozPS8I8q30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}