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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccaa4053a6e9580ee918bfab11b947a9557d7c27ebca5d9cd60f61df48fd9a3a' 
  AND token = 'QInA9DTGSK9iR2MzXo9Wl1pM+GLORBLGVi7mjMiG5uc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}