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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e5cc601335161e940b12026285853e0e18204442126e8b1be55ed46dd8947d4' 
  AND token = 'HGQb8XEo5Lhf99XrNJNlPp9x1sQ5LBqMjsJofX5kLlc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}