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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6180e07f3b59853a3582d121a388fe02d04411c0e964471adb5892c538480abe' 
  AND token = 'liNyO+OB0Jh8MXhdegMfjtDLFM2oTuR3M4sXkeERBFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}