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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad8206562145f7a533c3e5b7ea6b2188f6a219397698c4dc90a8964bcc68ea42' 
  AND token = 'XcLxGuM3W2v1dAWFROnm8KnLaAM6KMirnIwOQTh26gE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}