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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27286c2aa7a54c7d680d4af7ee449d455dc1be7c0cdb9099b3c47ea34d7830c4' 
  AND token = 'aZ0YoZQypUEHB/tMgVNkBoxRuWnN89zacOveGKqFx8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}