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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a45652734ffb614f938b9e88b1cd576d2e8c55500f1821e525c0cebd9f4d7c7' 
  AND token = 'CIFUaGt1ci7x17uU1+Nwxc2O5e7VsVhaAbd5yW+U46o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}