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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be45bd1efb3a770f9d54ce543561329a76d91b5a97059876c1f93e8830b779dc' 
  AND token = '66hFK6eFsNTb4Eui/Ena9XvEo+t451PGAjb8wELxUyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}