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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48d80658a5f3fa594f2b2b675c332acc12afca18033f903b0d8c5167507d529f' 
  AND token = 'FrE4j01Vx6NY6lsE670E6rU9nw6LCW2DRbn3ENF20ss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}