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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b846e38c693a8722e5d0219feff0264b45a81c2376bc3ebc6520b7c114e8cc5' 
  AND token = 'Z6BoicffynS9z2fuAdfdOAp/qgss2HgVcNdHkelgW8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}