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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b0518639d4b1725d9bfcacfbbaf7d262fef71bce7c0ba6344b4124b21f241b5' 
  AND token = 'NBX4o3jSHQa+1H/fub98jBZKrO9YTkxVSXtlUqdBZV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}