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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f3c6bb3130f4599e8e489c28dcf0f45630a9104fcc582dfd3d8ff6443172086' 
  AND token = 'Ol7huzm9uHi7fG6wdtcdzocZSRAt2xuYz+vqIMIKRkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}