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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '049bb41af58f381907d91de7c1f26f73e6ca17f15f383cc027245f12357e796a' 
  AND token = 'u5qkLrUQAmYTif1ic6pjzk06lp5M6XAfOAvYvcVv6nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}