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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43b698a9c34f30c148feba0fe29c1ccf05b7a6ca5c0f0a25bea1ebeab60970f7' 
  AND token = 'llXoCePxE6nEgTRvZGQ0kdcT5HA/Gd4Jig1WdS/UI6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}