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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f039264c631f3cbb766c92e191bbc72cc970091c2feacbb041d0c7cbd2e2105' 
  AND token = 'BpPXhx2g/PU2TMVtK7CLBL+1pnnMEuJfHNJW0XiTNJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}