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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbdd6e9c81d292fa2f6b5fbc03ee7982a08256485893b71d9ac999712e11229f' 
  AND token = 'IMNi+aq656drhJtk6zCqdu76LRT/QYRQyxaqVubhDeM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}