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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0508b2abb1d6bc8d269901dfdaa914aa8740b20491a143f1fcfab7b693043444' 
  AND token = 'IFKdzlQIn6c9foF2ajnWQRbSLQjnrDFDUIxm0wXNNUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}