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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4568aa572d1928cfb75557570abec453186252e861f3f548f73b24af438b32ab' 
  AND token = 'yvCiKh8Txo8Da8wpE9MXy+t5OBn41y9w3Y4h+uHH7DA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}