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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a29bae68cecb87dc4a67bb0d35e87e1e173b6c0f3f180d80006effadf2227a1' 
  AND token = 'lCHD8jetg0EIilJ1MbiutHBdANLgbVD86Y2+DlmM0BY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}