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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8f291c685ce2481e003995f9c8c25449f669dbb95b373525cfd343b917aeb03' 
  AND token = 'yKoPpcJfRn+he9V3BFr24l/ILcJZPen9auzgSR289bc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}