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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8469d454b5e0b4e58b623e219a220f149374a14e7db1c655c44d422d6a34aab1' 
  AND token = '8MZGdJli/r6s+RvOZQoRLrQCyE3tiQfz0tJRQ4n8xCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}