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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e7eb963d3eb041ffa988ba4d7b2e6dc0a19f50aa64a51e02b887621604c75ba' 
  AND token = 'JqGvVu2ZOnBUMO5O0ylgzbos/LUvk4mmKS5Ro49eFxo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}