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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22fe5db22a968c951c14dfc284ecfb9f0fc52f2a57125975a5de9eba4abe31c5' 
  AND token = 'KvOv5aJIF0/k2hVwMrTwaITFmY2J3F2pPmXqByl8/I4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}