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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e22a33f1718606db18d06d0bbca2a953d3f088efabbb0224b245bc2597f9fa55' 
  AND token = 'A9HLC5HGEpAEQW9uhbUCxxWGW0Aa5Bc8WQOW5wBRhtI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}