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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a622753e4948340f64605c7b980f05b1d15ec9150989c37910ba65af928a3f97' 
  AND token = 's0REQxVDNF8wD+/KUn+HroWVyKt0CxjTqGt6iWxoQbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}