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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e2feec3a6477ccd7bb2bb50b603f4dee5a113b6e4285f5596bb5e12f2807a33' 
  AND token = 'g7l9r2+CoSo7luR4kJvssXKskEVCQLzAngFAM9AYf6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}