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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f857ca9f8a9e0aed5d72dc719cbfad6c750b4c90026f46b0b58a3e80bc0bd1fd' 
  AND token = 'mOewwCjjGdqGex4NTPxf10R2DOi/KL+XVGPWpv4yl7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}