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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49e66ae62319719fd9f9eb147c67ff066d2a512baaab2f0df8e0e8dc24e3e2b7' 
  AND token = 'ld0nRLdhe3ps5MBzZ7nw4tQ7YsPfzJ1RjjM/COXTyXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}