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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d7381757ae096f584a2cef349880a013e1a4546f2acb14eaa7642e68a982c6c' 
  AND token = '4T27AH/4PTwuGH1ZkLSW4i8F/n3Sfne2hllR6uBG478=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}