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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '219e273cf66d7a38a6b101057ba6ec03927c40a3b8138374e5326c5544977e06' 
  AND token = 'upBUTO876Iq36Qxc972aEpYPior9aI/yXmyV2pCejUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}