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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd449944990a14290b2900b07467945fd0aed498b8a02dc693bad02c8e0088579' 
  AND token = 'szVZnsKTiO6ZgOpaYrlctZ6oUvAhiEs4k5aUHdRZAe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}