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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34356bbb2366c053e5fc7b79839b437dda2391cb5d684fdc0a93e35b28cb9b4b' 
  AND token = 'o8EovpRgbeN1st46tF+pn3pJu1o8IB6Vp6OYYmoJyFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}