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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '735ed392c26f1dcb18f4c1400306b8c2646a6a084ec45da7ff6de7be65dc4f5c' 
  AND token = '4Dko3kNFbcYytJhDm3rFgYPH0GZ5Z36Wz9c5VSSf48M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}