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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f72c34dacd6627245464182a415d3368f9cafd19e8e017852a08d79ccfa6552' 
  AND token = 'uL0cfDmB9JCctxKzCUB2HZFkUIUly6NLmDyG6AHlNKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}