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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '005294eb0609c505d3c60c931763c697266f04c05fc7b8a9e74d395cc6d7c8bb' 
  AND token = 'Q0Z2TXxQjUk0p4qGmVw0v8qTKc4vgKTYtxqsUPn9fEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}