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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bec94699a724b1921fcf30ac9ca7221cfc395c896a26015905e36f87279b10b' 
  AND token = 'amMuPF+pbNiHJq/1RHvO5Hk8xGXAy6etG9gY5ZPoYzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}