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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7c00c09e8e2a0b1e5bca4caf4e6a4b0f4e92a451d9b9e374e869260e42088d2' 
  AND token = 'WX9TkA1aaWYB2PWIe5/2fC0xywxhB2+nW/Q8JvRgyVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}