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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c6c294ca89a4b1c871aac0e7ce074588b0051e453575d4383012d8deede9b01' 
  AND token = '55TyVPX/aMG9DOVIWwTMpq/m442fgMcs5Ljx78oDX+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}