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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dc457c181ead14b3504e540a53b4859df7099cd3b1f9b4c049afb1e20e1d090' 
  AND token = 'Eg7hOBLdZSL7n2EX3OMcb9ThB8KkMXFSGkPjXUZLR4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}