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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c0446deebbe82f28d28719ff8dadd516288f0da1acddf696487c815393f407a' 
  AND token = '90UgyLeLVOkO97V9SHL1I8OrrqhFB0UqNORaBNcYf0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}