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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3747506d70fa86c9c5f490789cba2be86641a0aa36bb79c384d89d9b76769b2f' 
  AND token = 'Nt0IaYYWCSl06FPfzqD9J8q4aFfS5DeM9jbBWiuPULo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}