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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cde100958afea15845db7595820320956d7acf84c575c2b97c8af7fa294fec63' 
  AND token = 'xD8XlKSzAzr7ceaokDbo9E+zrcdw7pT8RGSmvUjk4S4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}