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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b11b8df9bdac947bdcdce1490384d431bc628a5682b83b7b6b4727fda26e42be' 
  AND token = 'hmz0GV28FFCbt7KRqUkUFSCE227TYzFH9jJNIMJ3nHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}