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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffae1108021bab04884f46a99ffa2d49b628a2531ad09759739b65d01a30468f' 
  AND token = 'U8KIzj2Fm4uHA6xeI/MmKi/UC0hTkIiOnr8TCa7vvz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}