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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64e44bd8468a5fd5e20a73b29e17aeb2ff39b6c6db06a61849a89f82375cf810' 
  AND token = 'GZFc5RGRU0TSuFxSlibcIr67Ecg2qbEfco6oRk9Bp8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}