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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7af7c2c4b255acd0668bbb0a82b2f84269afedc362b4524c126a72adc20e1ec' 
  AND token = 'PumsBcmaMyeWzEolPrC9olSI9D1Jml8UarrXuK72sp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}