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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f5db0e966c35ca4c2d71cc73864757980fb5d3038b06db6dcdab3adc46f8b65' 
  AND token = 'ulSUjypvWFwAVhGpvGEhpVU5crrE0ZDe11S/wU2khdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}